Vernon, Texas is at the crossroads of U.S. Highways 287 and 183. The town is located 61 miles east of Childress and 51 miles west of Wichita Falls on Highway 287. It is 21 miles south of the Oklahoma state line and 44 miles north of Seymour on 183.

The Pecan Grove Bed and Breakfast is located at 1904 Houston, four blocks west of Main Street (183) and on the second block south of Wilbarger Street. The house is between Marshall and Paradise Streets.